Detalhe da pesquisa
1.
Conserved transcriptional connectivity of regulatory T cells in the tumor microenvironment informs new combination cancer therapy strategies.
Nat Immunol
; 24(6): 1020-1035, 2023 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-37127830
2.
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
Cell
; 181(2): 424-441.e21, 2020 04 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-32234521
3.
The Oncogenic Action of NRF2 Depends on De-glycation by Fructosamine-3-Kinase.
Cell
; 178(4): 807-819.e21, 2019 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-31398338
4.
p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.
Cell
; 176(3): 564-580.e19, 2019 01 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-30580964
5.
The ectonucleotidase CD39 identifies tumor-reactive CD8+ T cells predictive of immune checkpoint blockade efficacy in human lung cancer.
Immunity
; 56(1): 93-106.e6, 2023 01 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36574773
6.
Metastatic Latency and Immune Evasion through Autocrine Inhibition of WNT.
Cell
; 165(1): 45-60, 2016 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-27015306
7.
Senescence-Induced Vascular Remodeling Creates Therapeutic Vulnerabilities in Pancreas Cancer.
Cell
; 184(18): 4838-4839, 2021 Sep 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-34478658
8.
Loss of the HVEM Tumor Suppressor in Lymphoma and Restoration by Modified CAR-T Cells.
Cell
; 167(2): 405-418.e13, 2016 Oct 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-27693350
9.
ARAF protein kinase activates RAS by antagonizing its binding to RASGAP NF1.
Mol Cell
; 82(13): 2443-2457.e7, 2022 07 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-35613620
10.
STING inhibits the reactivation of dormant metastasis in lung adenocarcinoma.
Nature
; 616(7958): 806-813, 2023 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-36991128
11.
Pan-KRAS inhibitor disables oncogenic signalling and tumour growth.
Nature
; 619(7968): 160-166, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37258666
12.
Diverse alterations associated with resistance to KRAS(G12C) inhibition.
Nature
; 599(7886): 679-683, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34759319
13.
Rapid non-uniform adaptation to conformation-specific KRAS(G12C) inhibition.
Nature
; 577(7790): 421-425, 2020 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-31915379
14.
Senescence induction dictates response to chemo- and immunotherapy in preclinical models of ovarian cancer.
Proc Natl Acad Sci U S A
; 119(5)2022 02 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35082152
15.
A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets.
Proc Natl Acad Sci U S A
; 119(17): e2110557119, 2022 04 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35442775
16.
Combined RAF and MEK Inhibition to Treat Activated Non-V600 BRAF-Altered Advanced Cancers.
Oncologist
; 29(1): 15-24, 2024 Jan 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-37616543
17.
Rapid interrogation of cancer cell of origin through CRISPR editing.
Proc Natl Acad Sci U S A
; 118(32)2021 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34353917
18.
Antitumor activity of the PI3K δ-sparing inhibitor MEN1611 in PIK3CA mutated, trastuzumab-resistant HER2 + breast cancer.
Breast Cancer Res Treat
; 199(1): 13-23, 2023 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-36913051
19.
Tumor-targeted nanoparticles improve the therapeutic index of BCL2 and MCL1 dual inhibition.
Blood
; 137(15): 2057-2069, 2021 04 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-33067607
20.
Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS.
Nature
; 548(7666): 234-238, 2017 08 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-28783719